Description

Boc-(R)-3-Amino-3-(2-Furyl)-Propionic Acid CAS NO 1217725-33-1 is a high-purity, non-natural amino acid derivative featuring a furan-protected side chain and a Boc-protected amine group. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling the introduction of unique structural motifs. It is primarily utilized by pharmaceutical and biotechnology research organizations for drug discovery, particularly in the development of novel enzyme inhibitors and therapeutic agents.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a furylalanine analog into peptide chains.
• Drug Discovery: Employed in medicinal chemistry for creating focused libraries and lead optimization candidates targeting various diseases.
• Bioconjugation: Acts as a specialized linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized to synthesize probes for studying protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Functions as a starting material or intermediate in the asymmetric synthesis of more complex chiral molecules.

Basic Information

Product Name	Boc-(R)-3-Amino-3-(2-Furyl)-Propionic Acid
CAS No.	1217725-33-1
Molecular Formula	C₁₂H₁₇NO₅
Molecular Weight	255.27 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid; Boc-D-β-(2-Furyl)-alanine; Boc-(R)-3-Amino-3-(2-furyl)propanoic acid; tert-Butyl (R)-3-amino-3-(furan-2-yl)propylcarbamate; (R)-2-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid; N-Boc-3-amino-3-(2-furyl)-(R)-propionic acid; Boc-β-(2-Furyl)-D-alanine
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-3-(2-Furyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.