Description

Fmoc-β-Imidazolyl-L-Ala is a specialized, non-proteinogenic amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for introducing the unique imidazole side chain, which is essential for creating peptides with specific catalytic or metal-binding properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides, enzyme inhibitors, and complex biomimetic materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, enabling the controlled assembly of complex peptide sequences.
• Biomimetic Catalyst Design: Used to incorporate histidine-like imidazole functionalities into synthetic peptides that mimic natural enzyme active sites.
• Pharmaceutical Research: Serves as a precursor in the development of peptide-based drugs targeting various diseases, where the imidazole group plays a role in binding or activity.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides for studying protein-protein interactions and enzymatic mechanisms.
• Material Science: Used to create functionalized peptides for advanced materials with specific chemical recognition properties.

Basic Information

Product Name	Fmoc-β-Imidazolyl-L-Ala
CAS No.	1217687-87-0
Molecular Formula	C22H21N3O4
Molecular Weight	391.42 g/mol
Synonyms	Fmoc-β-(1H-Imidazol-4-yl)-L-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(1H-imidazol-4-yl)-L-alanine; Fmoc-His(1)-OH (β-analogue); Fmoc-3-(4-Imidazolyl)-L-alanine; Fmoc-L-β-(4-Imidazolyl)alanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(1H-imidazol-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-β-Imidazolyl-L-Ala is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.