Description

(1R,2R,5R)-2-Isopropyl-5-Methylcyclohexanecarbonitrile is a high-purity, stereochemically defined chiral nitrile compound. It serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. This enantiomerically pure compound is essential for research and development chemists requiring precise stereochemical control to develop active ingredients with high efficacy and specificity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental safety.
• Flavor & Fragrance Chemistry: Acts as a precursor for the synthesis of specific terpene-derived aroma chemicals and flavoring agents.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and methodologies.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or mechanical properties.
• Academic & Industrial R&D: Serves as a standard or starting material for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(1R,2R,5R)-2-Isopropyl-5-Methylcyclohexanecarbonitrile
CAS No.	1217664-77-1
Molecular Formula	C11H19N
Molecular Weight	165.28 g/mol
Synonyms	(1R,2R,5R)-(-)-Menthonitrile; (1R,2R,5R)-2-Isopropyl-5-methylcyclohexane-1-carbonitrile; (-)-Menthonitrile; L-Menthonitrile; (1R,2R,5R)-Menthonitrile; (1R,2R,5R)-p-Menthane-1-carbonitrile; (1R,2R,5R)-1-Cyano-p-menthane
EINECS	Contact for details

Quality Control

Our (1R,2R,5R)-2-Isopropyl-5-Methylcyclohexanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure compliance with customer specifications and high industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.