Description

Elvucitabine-13C,15N2 is a stable isotope-labeled analog of the nucleoside reverse transcriptase inhibitor Elvucitabine, specifically enriched with carbon-13 and nitrogen-15 isotopes. This compound is an essential internal standard for the precise quantification and pharmacokinetic profiling of Elvucitabine in biological matrices using advanced analytical techniques like LC-MS/MS. It is a critical tool for pharmaceutical R&D, clinical research, and bioanalytical laboratories focused on antiviral drug development and metabolism studies.

Application

• Primary use as an internal standard for the accurate quantification of Elvucitabine in bioanalytical methods.
• Metabolite tracking and pharmacokinetic studies in preclinical and clinical research for antiviral therapies.
• Drug metabolism and disposition (DMPK) studies to understand absorption, distribution, metabolism, and excretion (ADME) pathways.
• Method development and validation in LC-MS/MS and other mass spectrometry-based assays.
• Quality control and assurance in the manufacturing of active pharmaceutical ingredients (APIs) and finished drug products.
• Supporting regulatory submissions to agencies like the FDA and EMA by providing definitive analytical data.

Basic Information

Product Name	Elvucitabine-13C,15N2
CAS No.	1217641-78-5
Molecular Formula	C7[13C]H11N3[15N]2O3
Molecular Weight	Contact for details
Synonyms	4-Amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone-13C,15N2; β-L-Fd4C-13C,15N2; ATC 3TC-13C,15N2; L-Fd4C-13C,15N2; (2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carbaldehyde-13C,15N2; 2'-Deoxy-3'-thia-5-fluorocytidine-13C,15N2; Isotopically Labeled Elvucitabine
EINECS	Contact for details

Quality Control

Our Elvucitabine-13C,15N2 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for critical research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic methods. We adhere to cGMP principles where applicable to support regulatory-driven research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C; ≥99 atom % 15N
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.