Description

(R)-1-Boc-3-(2-Aminoethyl)-Piperidine is a high-purity, chiral piperidine derivative protected with a tert-butoxycarbonyl (Boc) group. This compound is a critical chiral building block and intermediate in modern pharmaceutical synthesis, valued for its role in constructing complex molecular architectures. It is primarily required by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Peptidomimetic Chemistry: Used to introduce constrained, chiral amine functionalities into peptide backbones to enhance stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral scaffold or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and receptor interactions.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value fine chemicals and APIs.

Basic Information

Product Name	(R)-1-Boc-3-(2-Aminoethyl)-Piperidine
CAS No.	1217629-55-4
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-3-(2-Aminoethyl)-(R)-Piperidine; tert-Butyl (R)-3-(2-aminoethyl)piperidine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-3-(2-aminoethyl)piperidine; (R)-3-(2-Aminoethyl)piperidine-1-carboxylic acid tert-butyl ester; (R)-N-Boc-3-(2-Aminoethyl)piperidine; BOC-(R)-3-(2-Aminoethyl)piperidine; (R)-1-N-Boc-3-(2-Aminoethyl)piperidine; (R)-3-(2-Aminoethyl)-1-Boc-piperidine
EINECS	Contact for details

Quality Control

Our (R)-1-Boc-3-(2-Aminoethyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.