Description

Trans n-Benzyl Paroxetine-D4 CAS NO 1217614-37-3 is a high-purity, deuterium-labeled analog of the paroxetine derivative, serving as a critical internal standard in analytical chemistry. This compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in complex biological matrices. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development, pharmacokinetic studies, and quality control for active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of paroxetine and related compounds.
• Method Development and Validation in bioanalytical assays for drug metabolism and pharmacokinetics (DMPK) studies.
• Pharmaceutical Impurity Profiling and degradation pathway analysis.
• Metabolite Identification and tracking in preclinical and clinical research.
• Quality Control and Assurance testing for API manufacturers.
• Forensic and Clinical Toxicology analysis requiring high specificity.
• Stability-Indicating Assay development for pharmaceutical formulations.
• Isotope Dilution Mass Spectrometry (IDMS) for achieving definitive measurement accuracy.

Basic Information

Product Name	Trans n-Benzyl Paroxetine-D4
CAS No.	1217614-37-3
Molecular Formula	C19H16D4FNO3
Molecular Weight	Approx. 333.38 g/mol
Synonyms	Paroxetine D4 Benzyl Derivative; n-Benzylparoxetine-d4; (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-(phenyl-d4-methyl)piperidine; Deuterated Paroxetine Internal Standard; Paroxetine-d4 Benzyl Analog; Benzyl Paroxetine Isotopologue; 1-(Phenyl-d4-methyl)-4-(4-fluorophenyl)-3-[(1,3-benzodioxol-5-yloxy)methyl]piperidine
EINECS	Contact for details

Quality Control

Every batch of Trans n-Benzyl Paroxetine-D4 is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity, with specifications typically meeting or exceeding the requirements for certified reference materials (CRMs) and internal standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity (by HPLC), isotopic enrichment, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.