Description

(S)-2-Aminobutyramide-D3 Hydrochloride CAS NO 1217605-54-3 is a high-purity, deuterium-labeled isotopologue of (S)-2-aminobutyramide hydrochloride, serving as a critical stable isotope-labeled building block. This compound is essential for advanced research and development, providing a non-radioactive tracer for precise metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and contract development and manufacturing organizations (CDMOs) engaged in drug discovery and development.

Application

• Pharmaceutical Reference Standard: Used as an internal standard in quantitative LC-MS/MS and GC-MS analysis for method development and validation.
• Metabolic Pathway Tracing: Acts as a stable isotope-labeled tracer in drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic pathways.
• Biochemical Research: Employed in proteomics and metabolomics research to investigate amino acid and peptide biochemistry.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a chiral, labeled intermediate in the synthesis of novel deuterated drug candidates.
• Quality Control & Assurance: Critical for ensuring accuracy and precision in the quality control of related pharmaceutical compounds and impurities.

Basic Information

Product Name	(S)-2-Aminobutyramide-D3 Hydrochloride
CAS No.	1217605-54-3
Molecular Formula	C4H6D3ClN2O
Molecular Weight	139.58 g/mol
Synonyms	(2S)-2-Aminobutanamide-3,3,3-d3 Hydrochloride; (S)-2-Aminobutyramide-3,3,3-d3 HCl; (S)-2-Amino-3,3,3-trideuteriobutyramide Hydrochloride; (S)-α-Aminobutyramide-d3 Hydrochloride; L-2-Aminobutyramide-d3 Hydrochloride; (S)-2-Aminobutyric Acid Amide-d3 Hydrochloride; Deuterated (S)-2-Aminobutyramide HCl
EINECS	Contact for details

Quality Control

Our (S)-2-Aminobutyramide-D3 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and isotopic enrichment verification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.