Description

Boc-(4S,2Rs)-2-Ethylthiazolidine-4-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a thiazolidine ring and a Boc (tert-butoxycarbonyl) protecting group. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, stereochemically defined intermediates for peptide mimetics, protease inhibitors, and other complex target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetic Synthesis: Used to incorporate the constrained thiazolidine scaffold into peptide backbones, enhancing metabolic stability and bioavailability of peptide-based drug candidates.
• Chemical Biology Research: Employed as a building block for designing and synthesizing chemical probes and inhibitors to study enzyme function and biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to construct complex molecules with high enantiomeric purity.
• Fine Chemical Production: Serves as a specialized intermediate in the custom synthesis of complex organic compounds for various high-value industrial applications.

Basic Information

Product Name	Boc-(4S,2Rs)-2-Ethylthiazolidine-4-Carboxylic Acid
CAS No.	1217515-06-4
Molecular Formula	C11H19NO4S
Molecular Weight	261.34 g/mol
Synonyms	(4S,2Rs)-1-(tert-Butoxycarbonyl)-2-ethylthiazolidine-4-carboxylic acid; tert-Butyl (4S,2Rs)-2-ethyl-4-carboxythiazolidine-1-carboxylate; Boc-2-Et-Thz-OH; N-Boc-2-ethylthiazolidine-4-carboxylic acid; (2R,4S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-2-ethyl-1,3-thiazolidine-4-carboxylic acid; 1,3-Thiazolidine-4-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-2-ethyl-, (2R,4S)-; Boc-(2R,4S)-2-Ethylthiazolidine-4-Carboxylic Acid
EINECS	Contact for details

Quality Control

Our Boc-(4S,2Rs)-2-Ethylthiazolidine-4-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP manufacturing. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.