Description

15-Hydroxy Lubiprostone Dicyclohexylammonium Salt-D7 is a deuterated derivative of a key pharmaceutical intermediate, specifically designed for advanced research and development. This compound is of critical importance for use as an internal standard in mass spectrometry, enabling precise quantification and metabolic studies in pharmacokinetic and bioanalytical research. It is primarily required by pharmaceutical R&D laboratories, analytical service providers, and manufacturers of active pharmaceutical ingredients (APIs) focused on gastrointestinal therapeutics.

Application

• Primary use as a deuterated internal standard (IS) for the accurate quantification of lubiprostone and related metabolites in biological matrices via LC-MS/MS.
• Critical component in pharmacokinetic (PK) and bioequivalence studies to ensure data integrity and regulatory compliance.
• Facilitates drug metabolism and disposition (DMPK) research, aiding in the understanding of metabolic pathways.
• Enables high-precision analytical method development and validation for clinical and non-clinical testing.
• Supports quality control (QC) processes in API manufacturing where trace-level impurity profiling is required.
• Used in stable-isotope labeling studies to track molecular pathways and mechanisms of action.

Basic Information

Product Name	15-Hydroxy Lubiprostone Dicyclohexylammonium Salt-D7
CAS No.	1217511-55-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lubiprostone D7 derivative; 15-Hydroxy Lubiprostone-d7 Dicyclohexylamine Salt; Deuterated 15-Hydroxy Lubiprostone Salt; Dicyclohexylammonium 15-Hydroxy Lubiprostone-D7; (15S)-15-Hydroxy-9-oxoprosta-5,13-dien-1-oic Acid-d7 Dicyclohexylammonium Salt; AMITIZA Impurity D7; SPI-0213-D7 Salt; Internal Standard for Lubiprostone Quantification
EINECS	Contact for details

Quality Control

Our deuterated standards are manufactured under strict quality protocols to ensure the high isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is supported by comprehensive analytical data, including NMR and MS for structural confirmation and isotopic enrichment verification. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to expected mass spectrum
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms to structure
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.