Description

2-Bromo-4-Fluorophenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions. This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CROs and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-4-Fluorophenylboronic Acid
CAS No.	1217501-12-6
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(2-Bromo-4-fluorophenyl)boronic acid; 2-Bromo-4-fluorobenzeneboronic acid; B-(2-Bromo-4-fluorophenyl)boronic acid; 4-Fluoro-2-bromophenylboronic acid; 2-Bromo-4-fluorophenyl-Boronic Acid; Boronic acid, B-(2-bromo-4-fluorophenyl)-; 1217501-12-6
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluorophenylboronic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.