Description

Penicillin G-D7 Salt is a deuterated analog of the classic β-lactam antibiotic, Penicillin G. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is primarily utilized by pharmaceutical research and development laboratories, clinical research organizations, and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and quality control of antibiotic formulations.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Penicillin G and related compounds in complex biological matrices such as plasma, serum, and tissue homogenates.
• Pharmacokinetic and Bioavailability Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Metabolite Identification and Profiling: Aids in the detection and structural elucidation of drug metabolites using high-resolution mass spectrometry.
• Veterinary Drug Residue Analysis: Supports compliance testing in food safety programs to monitor antibiotic residues in meat, milk, and other animal products.
• Pharmaceutical Quality Control: Used in validated methods to assay the potency and purity of Penicillin G active pharmaceutical ingredients (APIs) and finished drug products.
• Environmental Monitoring: Facilitates the sensitive detection of penicillin contamination in water and environmental samples.

Basic Information

Product Name	Penicillin G-D7 Salt
CAS No.	1217445-37-8
Molecular Formula	C16H11D7N2O4S • (Na or K)
Molecular Weight	Contact for details
Synonyms	Benzylpenicillin-d7 Salt; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenyl-d5)acetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Sodium/Potassium Salt; Penicillin G Sodium-d7; Penicillin G Potassium-d7; Deuterated Penicillin G Salt; [D7]-Penicillin G Salt; Stable Isotope-Labeled Penicillin G
EINECS	Contact for details

Quality Control

Every batch of Penicillin G-D7 Salt is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and other critical specifications to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the product label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.