Description

5-Chloro Bifeprunox Mesylate is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the development and synthesis of novel antipsychotic agents, particularly as a key derivative of the partial dopamine agonist Bifeprunox. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in neuroscience and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting central nervous system disorders.
• Medicinal Chemistry Research: Used as a reference standard and precursor in the study of dopamine D2 receptor partial agonists for potential antipsychotic therapies.
• Process Development & Scale-Up: Serves as a key material for optimizing synthetic routes and scaling production of related pharmacologically active compounds.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, validation, and quality control of related substances.
• Preclinical Studies: Utilized in the preparation of compounds for in vitro and in vivo pharmacological evaluation.

Basic Information

Product Name	5-Chloro Bifeprunox Mesylate
CAS No.	1217042-05-1
Molecular Formula	C₂₀H₂₂ClN₃O₅S
Molecular Weight	451.92 g/mol
Synonyms	5-Chloro-7-[4-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone methanesulfonate; 5-Chloro Bifeprunox Methanesulfonate; DU-127090 Mesylate; UNII-6Q3B7B6S6R; Bifeprunox Impurity; Bifeprunox Related Compound
EINECS	Contact for details

Quality Control

Our 5-Chloro Bifeprunox Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.