Description

1-(4-tert-Butylphenyl)-4-[4-[(2,3,4,5,6-Pentadeuteriophenyl)-Phenylmethoxy]Piperidin-1-Yl]Butan-1-One is a high-purity, deuterated organic compound designed for advanced research and development. This deuterium-labeled analog is critical for applications requiring precise metabolic and pharmacokinetic studies, offering enhanced stability and traceability. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and contract research organizations (CROs) engaged in drug discovery and development.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantification and qualification of the parent compound in analytical methods.
• Metabolic Studies: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) profiling.
• Drug Discovery Research: Employed in mechanistic studies and as a tracer to investigate biological pathways and drug-receptor interactions without isotopic interference.
• Analytical Method Development: Essential for developing and validating highly sensitive and specific bioanalytical assays in compliance with Good Laboratory Practice (GLP).
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision quantitative analysis to ensure data accuracy and reliability.

Basic Information

Product Name	1-(4-tert-Butylphenyl)-4-[4-[(2,3,4,5,6-Pentadeuteriophenyl)-Phenylmethoxy]Piperidin-1-Yl]Butan-1-One
CAS No.	1216953-13-7
Molecular Formula	C32H35D5O2
Molecular Weight	467.70 g/mol (for deuterated form)
Synonyms	1-(4-tert-Butylphenyl)-4-[4-[(2,3,4,5,6-Pentadeuteriophenyl)-Phenylmethoxy]Piperidin-1-Yl]Butan-1-One-d5; Deuterated Loperamide Metabolite Standard; 4-[4-[(2,3,4,5,6-Pentadeuteriophenyl)phenylmethoxy]piperidin-1-yl]-1-(4-tert-butylphenyl)butan-1-one; Loperamide-d5 Related Compound; (4-tert-Butylphenyl)-4-[4-(pentadeuteriodiphenylmethoxy)piperidin-1-yl]butan-1-one
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and Mass Spectrometry. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and impurity profiles are provided to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.