Description

10-(T-Boc-Amino)-1-Decylmethanethiosulfonate is a specialized bifunctional chemical linker featuring a protected amine group and a thiosulfonate moiety, enabling controlled bioconjugation and surface functionalization. This compound is critical for researchers and manufacturers requiring precise, site-specific attachment of biomolecules, peptides, or probes to surfaces or other molecules. It is primarily utilized in advanced pharmaceutical development, proteomics research, and the creation of diagnostic assay platforms where reliable and reproducible conjugation chemistry is essential.

Application

• Bioconjugation Reagent: For the site-specific modification of proteins, antibodies, and peptides via disulfide bond formation.
• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on gold or other surfaces for biosensor and microarray development.
• Drug-Linker Conjugate Synthesis: Serves as a key intermediate in the construction of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Proteomics and Biomarker Discovery: Enables the immobilization or tagging of biomolecules for pull-down assays and affinity chromatography.
• Polymer and Material Science: Acts as a functional monomer or cross-linker for synthesizing smart polymers with cleavable or responsive properties.
• Diagnostic Kit Manufacturing: Employed in the production of lateral flow assays and ELISA kits where stable ligand attachment is required.

Basic Information

Product Name	10-(T-Boc-Amino)-1-Decylmethanethiosulfonate
CAS No.	1216932-86-3
Molecular Formula	C₁₆H₃₃NO₄S₂
Molecular Weight	367.56 g/mol
Synonyms	1-Decyl methanethiosulfonate, 10-[(1,1-Dimethylethoxy)carbonyl]amino]-; 10-((Tert-Butoxycarbonyl)amino)decyl methanethiosulfonate; Boc-NH-(CH₂)₁₀-SSO₂CH₃; S-Methyl 10-((tert-butoxycarbonyl)amino)decyl thiosulfonate; 10-(Boc-Amino)decyl methanethiosulfonate; T-Boc-Amino-decyl-MTS; (10-((tert-Butoxycarbonyl)amino)decyl) methanesulfonothioate
EINECS	Contact for details

Quality Control

Our 10-(T-Boc-Amino)-1-Decylmethanethiosulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and bioconjugation applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.