Description

3-Amino-1-Methyl-5H-Pyrido[4,3-β]Indole-13C2,15N Acetate is a stable isotope-labeled analog of a heterocyclic amine, specifically designed for advanced research and analytical applications. This compound is critical for use as an internal standard in mass spectrometry, enabling highly accurate quantification and metabolic pathway tracing in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) studies, toxicology research, and biomarker discovery.

Application

• Internal Standard for LC-MS/MS: Essential for precise quantitative bioanalysis in pharmacokinetic and toxicokinetic studies.
• Drug Metabolism Research: Used to trace and quantify metabolites, facilitating the understanding of biotransformation pathways.
• Biomarker Discovery and Validation: Enables accurate measurement of endogenous or exposure-related compounds in proteomic and metabolomic research.
• Environmental and Food Safety Testing: Supports the detection and quantification of trace-level heterocyclic aromatic amines (HAAs) in complex samples.
• Stable Isotope Labeling Studies: Serves as a tracer in mechanistic studies of chemical reactions and biological processes.
• Reference Material for Method Development: Provides a definitive standard for developing and validating new analytical methods in regulatory environments.

Basic Information

Product Name	3-Amino-1-Methyl-5H-Pyrido[4,3-β]Indole-13C2,15N Acetate
CAS No.	1216852-93-5
Molecular Formula	C1313C2H1515N3 • C2H4O2 (or specified acetate salt form)
Molecular Weight	Contact for details
Synonyms	Trp-P-2-13C2,15N Acetate; 3-Amino-1-methyl-5H-pyrido[4,3-b]indole-13C2,15N acetate; 1-Methyl-3-amino-5H-pyrido[4,3-b]indole-13C2,15N acetate; Isotopically labeled Trp-P-2 acetate; [13C2,15N]-3-Amino-1-methyl-5H-pyrido[4,3-b]indole acetate; Stable isotope-labeled heterocyclic amine; 13C2,15N-Trp-P-2 acetate
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-1-Methyl-5H-Pyrido[4,3-β]Indole-13C2,15N Acetate is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for sensitive analytical applications. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Off-white to light brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (MS)	≥ 98 atom % 13C, ≥ 98 atom % 15N
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.