Description

Rac Rasagiline-13C3 Mesylate is a stable isotope-labeled analog of the active pharmaceutical ingredient rasagiline, specifically enriched with carbon-13 at three positions. This compound is essential for use as an internal standard in quantitative bioanalytical methods, ensuring the highest accuracy and reliability in pharmacokinetic and metabolism studies. It is a critical tool for pharmaceutical researchers, analytical laboratories, and contract research organizations (CROs) engaged in drug development and regulatory compliance for neurological therapies.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the precise measurement of rasagiline and its metabolites in biological matrices.
• Pharmacokinetic (PK) Studies: Enables accurate determination of drug absorption, distribution, metabolism, and excretion (ADME) profiles during preclinical and clinical development.
• Metabolite Identification & Profiling: Aids in the structural elucidation and quantification of metabolite formation pathways.
• Bioequivalence & Bioanalytical Method Validation: Critical for validating analytical methods to meet FDA, EMA, and ICH guidelines for drug approval.
• Doping Control & Forensic Analysis: Used in specialized testing protocols where precise quantification of rasagiline or related compounds is required.
• Stable Isotope Dilution Assays (SIDA): Provides the foundation for highly accurate and precise quantification techniques in complex samples.

Basic Information

Item	Detail
Product Name	Rac Rasagiline-13C3 Mesylate
CAS No.	1216757-55-9
Molecular Formula	C₁₂H₁₅N•13C₃•CH₄O₃S
Molecular Weight	Contact for details
Synonyms	(Rac)-Rasagiline-13C3 Mesylate; 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-13C3-, methanesulfonate; Rasagiline-13C3 (racemic) mesylate salt; Rasagiline-13C3 Mesylate (racemic); N-Propargyl-1(R,S)-aminoindan-13C3 Mesylate; Azilect-13C3 Mesylate (racemic); TVP-1012-13C3 Mesylate (racemic)
EINECS	Contact for details

Quality Control

Every batch of Rac Rasagiline-13C3 Mesylate is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed using advanced techniques including NMR, HPLC, and LC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data for identity, purity (HPLC), isotopic enrichment, and residual solvents to meet the stringent requirements of analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (by NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.