Description

Harman-D3 is a high-purity, deuterated chemical compound used as a critical intermediate and reference standard in advanced research and development. Its precise isotopic labeling makes it an essential tool for metabolic studies, pharmacokinetic research, and analytical method development. This product is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of diagnostic agents requiring stable isotope-labeled materials.

Application

• Pharmaceutical Research: As a stable isotope-labeled internal standard for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) bioanalysis.
• Metabolite Identification: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and identify metabolite pathways.
• Proteomics & Biomarker Discovery: Serves as a reagent in quantitative proteomics workflows for precise protein and peptide measurement.
• Diagnostic Agent Synthesis: An intermediate in the synthesis of deuterated contrast agents or probes for advanced imaging techniques like Magnetic Resonance Imaging (MRI).
• Chemical Reference Standard: Provides a certified reference material for calibrating analytical instruments and validating testing methods in quality control laboratories.
• Academic Research: Enables mechanistic studies in chemistry and biochemistry where tracing molecular pathways is required.

Basic Information

Product Name	Harman-D3
CAS No.	1216708-84-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Deuterated Harman; Harman-d3; 1-Methyl-9H-pyrido[3,4-b]indole-d3; Norharman-D3 (methyl-d3); 9H-Pyrido[3,4-b]indole, 1-methyl-d3
EINECS	Contact for details

Quality Control

Every batch of Harman-D3 is manufactured and tested under strict quality management systems to ensure identity, purity, and isotopic enrichment meet the highest standards for research use. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic analyses. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Related Substances (HPLC)	≤ 1.0% total
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.