Description

Desisopropyl Disopyramide Oxalate is a high-purity pharmaceutical intermediate and reference standard of significant importance in modern chemical synthesis and analytical research. Its primary value lies in its role as a key metabolite and synthetic precursor for the development and quality control of antiarrhythmic agents. This compound is essential for research institutions, pharmaceutical manufacturers, and analytical laboratories focused on cardiovascular drug development, metabolism studies, and regulatory compliance testing.

Application

• Pharmaceutical Intermediate: Critical synthetic building block in the production of advanced antiarrhythmic drug candidates and their analogs.
• Analytical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of disopyramide and its metabolites in biological matrices and pharmaceutical formulations via HPLC, LC-MS, or GC-MS.
• Metabolism and Pharmacokinetic Studies: Serves as a standard for investigating the metabolic pathways, bioavailability, and clearance of disopyramide in preclinical and clinical research.
• Impurity Profiling: Employed in the identification and control of process-related impurities and degradation products in active pharmaceutical ingredient (API) manufacturing, ensuring compliance with ICH guidelines.
• Academic and Contract Research: Utilized in university and CRO settings for methodological development, teaching, and investigative studies in medicinal chemistry and pharmacology.

Basic Information

Product Name	Desisopropyl Disopyramide Oxalate
CAS No.	1216619-15-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Desisopropyl Disopyramide Oxalate; N-Desisopropyl Disopyramide Oxalate; Disopyramide Desisopropyl Metabolite Oxalate; α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide N-Desisopropyl Oxalate; Nor-Disopyramide Oxalate; Mono-Desisopropyl Disopyramide Oxalate
EINECS	Contact for details

Quality Control

Our Desisopropyl Disopyramide Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing comprehensive test results, including assay by HPLC and related substance analysis, are provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.