Description

3-Benzyloxy-α-(n-Butyryl-D3)-Aminopropionitrile is a deuterated organic compound of significant interest in advanced chemical synthesis and research. This molecule serves as a crucial building block for the development of isotopically labeled compounds, enabling precise metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers specializing in the production of deuterated active pharmaceutical ingredients (APIs) and sophisticated intermediates.

Application

• Deuterated Pharmaceutical Intermediate: A key precursor in the synthesis of deuterium-labeled drug candidates for enhanced metabolic stability and improved pharmacokinetic profiles.
• Metabolic Pathway Tracer: Used in drug discovery and development to trace and analyze metabolic pathways using mass spectrometry and NMR techniques.
• Isotope Labeling Agent: Employed in the preparation of isotopically labeled standards for quantitative bioanalytical assays and environmental testing.
• Advanced Organic Synthesis: Serves as a specialized synthon in complex multi-step organic syntheses, particularly for molecules containing nitrile and protected amino functionalities.
• Proteomics & Biochemistry Research: Utilized in the development of chemical probes and tools for studying protein interactions and enzymatic mechanisms.

Basic Information

Item	Detail
Product Name	3-Benzyloxy-α-(n-Butyryl-D3)-Aminopropionitrile
CAS No.	1216615-94-9
Molecular Formula	C14H16D3N2O2
Molecular Weight	247.33 g/mol
Synonyms	3-(Benzyloxy)-α-[(2,2,3,3,3-pentadeuterio-1-oxobutyl)amino]propanenitrile; α-[(Butyryl-d3)amino]-3-(phenylmethoxy)propanenitrile; 3-Benzyloxy-α-(butyryl-d3-amino)propionitrile; Deuterated Butyryl Aminopropionitrile Derivative; (3-Benzyloxy-2-cyanoethyl)(butyryl-d3)amine; BNBP-d3; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-α-(n-Butyryl-D3)-Aminopropionitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ²H) and HPLC, to ensure high chemical and isotopic purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, isotopic enrichment, and impurity profile is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (²H NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.