Description

n-Desethyl-n-Propyl Oxybutynin CAS NO 1215677-72-7 is a high-purity pharmaceutical intermediate and a key structural analog of oxybutynin, a well-established antimuscarinic agent. This compound is of significant value in the research and development of novel therapeutics targeting overactive bladder (OAB) and other urological disorders. It serves as a critical building block for medicinal chemists and pharmaceutical manufacturers engaged in synthesizing new chemical entities (NCEs) and developing improved drug delivery systems. Its precise structure allows for targeted modifications to study structure-activity relationships (SAR) and optimize pharmacological profiles.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the production of oxybutynin analogs and next-generation antimuscarinic drugs.
• Medicinal Chemistry Research: Essential for structure-activity relationship (SAR) studies aimed at enhancing efficacy and reducing side effects of urological therapeutics.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up of new API candidates for overactive bladder (OAB) treatment.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and analytical method development in pharmaceutical laboratories.
• Drug Delivery System Research: Incorporated into studies for transdermal patches, controlled-release formulations, and other advanced delivery mechanisms.
• Metabolite Studies: Utilized in pharmacological and toxicological research to understand drug metabolism pathways.

Basic Information

Product Name	n-Desethyl-n-Propyl Oxybutynin
CAS No.	1215677-72-7
Molecular Formula	C22H31NO3
Molecular Weight	357.49 g/mol
Synonyms	4-(Diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate (Propyl Analog); Desethylpropyl Oxybutynin; Oxybutynin N-Desethyl-N-Propyl Analog; α-Cyclohexyl-α-hydroxybenzenacetic acid 4-(diethylamino)-2-butynyl ester (propyl variant); N-Propyl-N-desethyl oxybutynin; Oxybutynin Impurity/Intermediate; (±)-4-(Diethylamino)but-2-ynyl α-cyclohexyl-α-hydroxybenzeneacetate (propyl form)
EINECS	Contact for details

Quality Control

Our n-Desethyl-n-Propyl Oxybutynin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for intermediates, ensuring traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.