Description

2-Amino-1-(4’-Methoxy-3’-Sulfonamidophenyl)-2-Propanone-D3 Hydrochloride is a high-purity, deuterated chemical building block and reference standard. This compound matters for its critical role in advanced pharmaceutical research, particularly in the development and validation of analytical methods for drug metabolism and pharmacokinetic (DMPK) studies. It is primarily needed by research scientists and process chemists in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors working on novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as an internal standard for the precise quantification of its non-deuterated counterpart in complex biological matrices via LC-MS/MS.
• Metabolic Studies: Employed in drug metabolism and pharmacokinetic (DMPK) research to track and differentiate exogenous compounds from endogenous metabolites.
• Process Chemistry & Impurity Profiling: Serves as a critical marker in the development and optimization of synthetic routes and for identifying process-related impurities.
• Bioanalytical Method Development: Essential for validating sensitive and accurate analytical methods in compliance with GLP and ICH guidelines.
• Stable Isotope Labeling: Acts as a deuterium-labeled precursor or intermediate in the synthesis of more complex isotopically labeled target molecules.

Basic Information

Product Name	2-Amino-1-(4’-Methoxy-3’-Sulfonamidophenyl)-2-Propanone-D3 Hydrochloride
CAS No.	1215568-62-9
Molecular Formula	C11H12D3ClN2O4S
Molecular Weight	309.80 g/mol
Synonyms	2-Amino-1-(4-methoxy-3-sulfamoylphenyl)propan-1-one-d3 hydrochloride; 1-(4-Methoxy-3-sulfonamidophenyl)-2-aminopropanone-d3 HCl; 2-Amino-1-(4-methoxy-3-sulfamoylphenyl)-2-propanone-d3 hydrochloride; Deuterated Sulfonamide Ketone Hydrochloride; α-Aminopropiophenone-d3 derivative hydrochloride; (4-Methoxy-3-sulfamoylphenyl)-2-aminopropanone-d3 hydrochloride; 2-Amino-1-(3-sulfamoyl-4-methoxyphenyl)propan-1-one-d3 hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4’-Methoxy-3’-Sulfonamidophenyl)-2-Propanone-D3 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and deuterium enrichment analysis, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, isotopic purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.