Description

5-Amino-2-Bromo-4-Chlorobenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates amino, bromo, chloro, and cyano functional groups, enabling precise and versatile chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, color-fast organic dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and cyanation reactions due to the reactive bromo and chloro substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Amino-2-Bromo-4-Chlorobenzonitrile
CAS No.	1215206-56-6
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	2-Bromo-4-chloro-5-aminobenzonitrile; 4-Chloro-5-amino-2-bromobenzonitrile; 5-Amino-2-bromo-4-chlorobenzene carbonitrile; Benzonitrile, 5-amino-2-bromo-4-chloro-; 2-Bromo-4-chloro-5-cyanoaniline
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Bromo-4-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.