Description

3-Bromo-5-(Methylsulfonyl)Benzotrifluoride is a high-value, multi-functional aromatic building block characterized by its bromine, trifluoromethyl, and methylsulfonyl substituents. This unique combination of electron-withdrawing groups makes it an essential intermediate for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including kinase inhibitors and other biologically relevant compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorinated structure.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic systems.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligands in organometallic chemistry and catalysis.

Basic Information

Product Name	3-Bromo-5-(Methylsulfonyl)Benzotrifluoride
CAS No.	1215205-96-1
Molecular Formula	C8H5BrF3O2S
Molecular Weight	303.09 g/mol
Synonyms	1-Bromo-3-(methylsulfonyl)-5-(trifluoromethyl)benzene; 3-Bromo-5-(trifluoromethyl)phenyl methyl sulfone; 5-Bromo-α,α,α-trifluoro-m-(methylsulfonyl)toluene; 3-Bromo-5-(methylsulfonyl)benzotrifluoride; 3-Bromo-α,α,α-trifluoro-5-(methylsulfonyl)toluene; Benzene, 1-bromo-3-(methylsulfonyl)-5-(trifluoromethyl)-; [1215205-96-1]
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(Methylsulfonyl)Benzotrifluoride is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.