Description

(2-Bromo-5-Fluorophenyl)Acetic Acid Ethyl Ester is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound is valued for its dual halogen functionality, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other advanced functional materials requiring halogenated aromatic cores.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings.
• Chemical Derivatization: The ester group allows for further functionalization via hydrolysis, reduction, or transesterification to access a wide array of carboxylic acid derivatives.

Basic Information

Product Name	(2-Bromo-5-Fluorophenyl)Acetic Acid Ethyl Ester
CAS No.	1214910-61-8
Molecular Formula	C10H10BrFO2
Molecular Weight	261.09 g/mol
Synonyms	Ethyl (2-Bromo-5-fluorophenyl)acetate; 2-Bromo-5-fluorobenzeneacetic acid ethyl ester; (2-Bromo-5-fluorophenyl)acetic acid ethyl ester; Ethyl 2-(2-bromo-5-fluorophenyl)acetate; α-(2-Bromo-5-fluorophenyl)acetic acid ethyl ester; 2-Bromo-5-fluoro-α-phenylacetic acid ethyl ester; Benzeneacetic acid, 2-bromo-5-fluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of (2-Bromo-5-Fluorophenyl)Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.