Description

2-Amino-3-Methyl-n-[2-(4-Morpholinyl)Ethyl]-Pentanamide Dihydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including potential protease inhibitors or GPCR modulators.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design and synthesis of peptide mimics to enhance metabolic stability and bioavailability.
• Chemical Biology Probe Development: Used to create labeled or modified compounds for studying enzyme mechanisms and protein-ligand interactions.
• Agrochemical Synthesis: Acts as a precursor in the development of novel, high-efficacy crop protection agents with specific modes of action.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for asymmetric catalysis or metal complexation.
• Academic and Institutional Research: Provides a valuable tool for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	2-Amino-3-Methyl-n-[2-(4-Morpholinyl)Ethyl]-Pentanamide Dihydrochloride
CAS No.	1214672-15-7
Molecular Formula	C13H28N4O2 · 2HCl
Molecular Weight	353.31 g/mol (Free base: 272.39 g/mol)
Synonyms	L-Isoleucine, N-[2-(4-morpholinyl)ethyl]-, amide, dihydrochloride; (2S,3S)-2-Amino-3-methyl-N-[2-(morpholin-4-yl)ethyl]pentanamide dihydrochloride; 2-Amino-3-methyl-N-(2-morpholin-4-ylethyl)pentanamide dihydrochloride; UNII-9J0G8A6R4F; 9J0G8A6R4F; SCHEMBL23306231; BDBM50389373; AKOS025147269
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methyl-n-[2-(4-Morpholinyl)Ethyl]-Pentanamide Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.