Description

4-Fluoro-2-Methoxybiphenyl is a high-purity fluorinated biphenyl derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a methoxy and a fluorine substituent on the biphenyl scaffold, enabling precise electronic and steric modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Acts as a core component or side-chain modifier in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials due to its favorable electronic properties.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create diverse biaryl libraries for screening.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with enhanced thermal and chemical resistance.

Basic Information

Item	Details
Product Name	4-Fluoro-2-Methoxybiphenyl
CAS No.	1214387-67-3
Molecular Formula	C₁₃H₁₁FO
Molecular Weight	202.23 g/mol
Synonyms	2-Methoxy-4-fluorobiphenyl; 4-Fluoro-2-methoxy-1,1'-biphenyl; [1,1'-Biphenyl]-4-fluoro-2-methoxy-; 4-Fluoro-2-phenylanisole; 2-Methoxy-4-phenylfluorobenzene; 4-Fluoro-2-methoxy diphenyl
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxybiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.