Description

4-Chloro-2-(Trifluoromethyl)-4-Chloro-2-(Trifluoromethyl)-1,1-Biphenyl is a specialized biphenyl derivative featuring chloro and trifluoromethyl substituents, making it a valuable fluorinated aromatic building block. This compound is engineered to provide a unique combination of lipophilicity and electronic properties, which is critical for advanced material and pharmaceutical synthesis. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Active Ingredient Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Development: Acts as a core or side-chain unit in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and thermal stability.
• Polymer & Resin Modifier: Incorporated into high-performance polymers to impart specific characteristics like chemical resistance, low surface energy, or altered refractive index.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to construct complex, multi-ring fluorinated architectures.
• Catalyst Ligand Precursor: Provides a scaffold for developing novel ligands in transition metal catalysis for asymmetric synthesis.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)-4-Chloro-2-(Trifluoromethyl)-1,1-Biphenyl
CAS No.	1214387-07-1
Molecular Formula	C14H7Cl2F3
Molecular Weight	303.11 g/mol
Synonyms	1,1'-Biphenyl, 4-chloro-2-(trifluoromethyl)-4-chloro-2-(trifluoromethyl)-; 4,4'-Dichloro-2,2'-bis(trifluoromethyl)biphenyl; 2,2'-Bis(trifluoromethyl)-4,4'-dichlorobiphenyl; 4,4'-Dichloro-α,α,α,α',α',α'-hexafluoro-o,o'-bitolyl; 4-Chloro-2-(trifluoromethyl)biphenyl-4'-chloro-2'-(trifluoromethyl) derivative
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethyl)-4-Chloro-2-(Trifluoromethyl)-1,1-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, and our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.