Description

3-Methoxy-2-(Trifluoromethyl)Benzonitrile, 97% is a high-purity aromatic nitrile derivative featuring both methoxy and trifluoromethyl substituents. This compound is a valuable advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano group transformations to introduce complex functionalities into target molecules.
• Fluorine Chemistry Research: An important reagent for studying the effects of fluorine substitution on molecular conformation, lipophilicity, and binding affinity in medicinal chemistry.

Basic Information

Product Name	3-Methoxy-2-(Trifluoromethyl)Benzonitrile, 97%
CAS No.	1214385-02-0
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	2-(Trifluoromethyl)-3-methoxybenzonitrile; 3-Methoxy-2-(trifluoromethyl)benzonitrile; 2-Cyano-6-methoxybenzotrifluoride; 2-Methoxy-6-(trifluoromethyl)benzonitrile; Benzonitrile, 3-methoxy-2-(trifluoromethyl)-; 1214385-02-0; α,α,α-Trifluoro-3-methoxy-o-tolunitrile
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2-(Trifluoromethyl)Benzonitrile, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.