Description

3-Methoxy-4-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both a methoxy and a trifluoromethyl group on the phenyl ring, makes it a critical intermediate for creating compounds with tailored electronic and steric properties. This product is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylphenyl moiety to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group contributes to efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a starting material for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes due to its influence on polarity and mesomorphic properties.
• Functional Material Research: Used in academic and industrial R&D to create novel polymers, ligands for catalysis, and specialty chemicals with specific fluorinated architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized fluorinated intermediates.

Basic Information

Item	Detail
Product Name	3-Methoxy-4-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1214372-99-2
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	4-(Trifluoromethyl)-3-methoxyphenylacetonitrile; 2-[3-Methoxy-4-(trifluoromethyl)phenyl]acetonitrile; (3-Methoxy-4-trifluoromethylphenyl)acetonitrile; 3-Methoxy-α,α,α-trifluoro-p-toluacetonitrile; 4-Cyanoethyl-2-methoxybenzotrifluoride; 1-Methoxy-2-(trifluoromethyl)-4-cyanomethylbenzene; [3-Methoxy-4-(trifluoromethyl)phenyl]acetonitrile
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-(Trifluoromethyl)Phenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.