Description

3-Bromo-4-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research, where the introduction of bromine and trifluoromethyl groups is strategically important. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the trifluoromethyl and bromine substituents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1214372-42-5
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-(3-Bromo-4-(trifluoromethyl)phenyl)acetonitrile; (3-Bromo-4-(trifluoromethyl)phenyl)acetonitrile; 3-Bromo-α,α,α-trifluoro-p-toluacetonitrile; 2-(3-Bromo-4-(trifluoromethyl)phenyl)ethanenitrile; 3-Bromo-4-trifluoromethylbenzyl cyanide; 3-Bromo-4-(trifluoromethyl)benzyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(Trifluoromethyl)Phenylacetonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC/GC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.