Description

2-(3-Methyl-4-(Trifluoromethyl)Phenyl)Acetic Acid is a high-value fluorinated aromatic building block, prized for its unique structural motif that combines a phenylacetic acid core with a trifluoromethyl group. This compound matters for its critical role in facilitating the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the trifluoromethyl group is known to enhance metabolic stability, lipophilicity, and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry, lead optimization, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in areas like oncology, CNS disorders, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the CF3 group contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to impart specific properties like chemical resistance or altered refractive index in high-performance polymers.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development and the synthesis of novel fluorinated compounds for various applications.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific fluorinated aromatic acid scaffold.

Basic Information

Product Name	2-(3-Methyl-4-(Trifluoromethyl)Phenyl)Acetic Acid
CAS No.	1214360-33-4
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	[3-Methyl-4-(trifluoromethyl)phenyl]acetic acid; 2-(3-Methyl-4-(trifluoromethyl)phenyl)ethanoic acid; 2-(3-Methyl-4-trifluoromethylphenyl)acetic Acid; α-(3-Methyl-4-(trifluoromethyl)phenyl)acetic acid; (3-Methyl-4-trifluoromethylphenyl)acetic acid; 4-Trifluoromethyl-m-tolylacetic acid; 2-(3-Methyl-4-trifluoromethylphenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Methyl-4-(Trifluoromethyl)Phenyl)Acetic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. While produced to meet general reagent-grade standards, specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.