Description

(2,3-Difluorophenyl)Methanaminehydrochloride is a high-purity fluorinated aromatic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the (2,3-difluorophenyl)methanamine pharmacophore into target molecules, enabling the development of compounds with tailored biological and physicochemical properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the difluorophenyl moiety enhances activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under GMP or non-GMP conditions.

Basic Information

Product Name	(2,3-Difluorophenyl)Methanaminehydrochloride
CAS No.	1214350-73-8
Molecular Formula	C7H8ClF2N
Molecular Weight	179.59 g/mol
Synonyms	(2,3-Difluorobenzyl)amine hydrochloride; 1-(2,3-Difluorophenyl)methanamine hydrochloride; 2,3-Difluorobenzylamine hydrochloride; α-Amino-2,3-difluorotoluene hydrochloride; Benzenemethanamine, 2,3-difluoro-, hydrochloride; (2,3-Difluorophenyl)methylamine HCl
EINECS	Contact for details

Quality Control

Our (2,3-Difluorophenyl)Methanaminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.