Description

2-Bromo-3-(Trifluoromethyl)Phenylacetonitrile is a high-value, multi-functional chemical intermediate characterized by its bromine and trifluoromethyl substituents on the aromatic ring. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced synthesis in demanding research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for carbon-carbon bond formation.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and metal-organic frameworks (MOFs) with tailored properties.
• Fluorine Chemistry Studies: A valuable reagent for investigating the effects of fluorine substitution on molecular reactivity and physical characteristics.

Basic Information

Product Name	2-Bromo-3-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1214339-44-2
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-Bromo-3-(trifluoromethyl)benzyl cyanide; (2-Bromo-3-(trifluoromethyl)phenyl)acetonitrile; α-Cyano-2-bromo-3-(trifluoromethyl)toluene; 2-Bromo-3-trifluoromethylphenylacetonitrile; 2-Bromo-α-cyano-3-(trifluoromethyl)toluene; Benzeneacetonitrile, 2-bromo-3-(trifluoromethyl)-; 3-Trifluoromethyl-2-bromobenzyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.