Description

4-(Difluoromethoxy)-1-Fluoro-2-Methyl-Benzene is a specialized fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the difluoromethoxy and fluoro substituents, which are crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoromethoxy group can enhance biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a fluorinated component in the synthesis of specialty chemicals for electronic displays, leveraging its aromatic structure and fluorine content.
• Organic Electronics: Potential building block for materials used in organic light-emitting diodes (OLEDs) and semiconductors due to its electronic properties.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new reactions in fluoroorganic chemistry.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing tailored compounds for client projects.

Basic Information

Product Name	4-(Difluoromethoxy)-1-Fluoro-2-Methyl-Benzene
CAS No.	1214333-46-6
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	1-Fluoro-2-methyl-4-(difluoromethoxy)benzene; 4-(Difluoromethoxy)-2-fluorotoluene; 2-Fluoro-α,α-difluoro-4-methylanisole; 1-Fluoro-4-(difluoromethoxy)-2-methylbenzene; Benzene, 4-(difluoromethoxy)-1-fluoro-2-methyl-; DFMFB (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 4-(Difluoromethoxy)-1-Fluoro-2-Methyl-Benzene is produced and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with exacting research and synthesis standards. Comprehensive Certificates of Analysis (COA) with batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.