Description

3'-Fluoro-5-Methoxy-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative, distinguished by its strategically placed fluorine and methoxy substituents. This compound is a critical pharmaceutical intermediate and organic building block for advanced synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides and fungicides, leveraging the bioactivity of the biphenyl core.
• Ligand Synthesis: Used in medicinal chemistry for creating novel ligands in drug discovery programs, especially where fluorine substitution is desired for metabolic stability.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and liquid crystals.
• Chemical Research: Employed in academic and industrial R&D for cross-coupling reactions and as a model compound in methodological studies.

Basic Information

Product Name	3'-Fluoro-5-Methoxy-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1214324-49-8
Molecular Formula	C14H11FO3
Molecular Weight	246.23 g/mol
Synonyms	3'-Fluoro-5-methoxybiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-5-methoxy-; 3-(3-Fluoro-5-methoxyphenyl)benzoic acid; 3'-Fluoro-5'-methoxybiphenyl-3-carboxylic acid; 5-Methoxy-3'-fluorobiphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-5-Methoxy-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.