Description

n-(3-Methoxypropyl) Dl-Z-Phenylalaninamide is a protected amino acid derivative, specifically a phenylalanine amide modified with a Z-protecting group and a 3-methoxypropyl side chain. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides and pharmaceutical active ingredients, offering versatility for medicinal chemistry research and process development. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of peptide-based drugs and small molecule pharmaceuticals.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of enzyme inhibitors or receptor modulators.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Utilized as a probe or tool compound for studying biological processes and protein interactions.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industries.

Basic Information

Product Name	n-(3-Methoxypropyl) Dl-Z-Phenylalaninamide
CAS No.	1214193-95-9
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	DL-Z-Phenylalaninamide, N-(3-Methoxypropyl)-; Benzyloxycarbonyl-DL-phenylalanyl-3-methoxypropylamide; Z-DL-Phe-NH-(CH2)3OCH3; N-(3-Methoxypropyl)-N-[(benzyloxy)carbonyl]-DL-phenylalaninamide; (RS)-2-[(Benzyloxycarbonyl)amino]-3-phenyl-N-(3-methoxypropyl)propanamide; 3-Phenyl-2-{[(phenylmethoxy)carbonyl]amino}-N-(3-methoxypropyl)propanamide; DL-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, 3-methoxypropylamide
EINECS	Contact for details

Quality Control

Our n-(3-Methoxypropyl) Dl-Z-Phenylalaninamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-Racemate
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.