Description

(tert-Butoxy)Carbonyl L-2-Chloro-4-Fluorophe is a high-purity, non-natural amino acid derivative characterized by its chiral center and halogenated aromatic side chain. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Peptide Chemistry: Employed in solid-phase and solution-phase peptide synthesis to incorporate halogenated phenylalanine analogs into peptide sequences.
• Proteomics & Biochemistry: Acts as a substrate analog or a labeled precursor in metabolic pathway studies and enzyme mechanism investigations.
• Material Science: Potential monomer for creating specialized polymers with unique optical or electronic properties derived from its aromatic and halogenated structure.

Basic Information

Product Name	(tert-Butoxy)Carbonyl L-2-Chloro-4-Fluorophe
CAS No.	1213887-81-0
Molecular Formula	C14H17ClFNO4
Molecular Weight	317.74 g/mol
Synonyms	Boc-L-2-Chloro-4-fluorophenylalanine; N-Boc-2-Chloro-4-fluoro-L-phenylalanine; N-(tert-Butoxycarbonyl)-2-chloro-4-fluoro-L-phenylalanine; Boc-2-Cl-4-F-Phe-OH; (2S)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-(2-chloro-4-fluorophenyl)propanoic acid; 2-Chloro-4-fluoro-L-phenylalanine N-Boc derivative; Fmoc-L-2-Chloro-4-Fluorophe precursor
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl L-2-Chloro-4-Fluorophe is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.