Description

(R)-2-(-1-Amino-Ethyl)-Benzonitrile CAS NO 1213885-82-5 is a chiral benzonitrile derivative featuring a primary amine functional group, making it a versatile and valuable chiral building block in advanced organic synthesis. Its enantiopure nature is critical for the development of pharmaceuticals and agrochemicals where stereochemistry directly influences biological activity and efficacy. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and other complex chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where the specific (R)-enantiomer can offer superior activity and environmental profile.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating complex, high-value specialty chemicals.
• Academic & Industrial Research: A valuable compound for methodological development in asymmetric synthesis and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	(R)-2-(-1-Amino-Ethyl)-Benzonitrile
CAS No.	1213885-82-5
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	(R)-2-(1-Aminoethyl)benzonitrile; (R)-α-Methyl-2-cyanobenzylamine; (R)-1-(2-Cyanophenyl)ethylamine; (R)-2-(1-Aminoethyl)benzenecarbonitrile; (R)-2-Cyanobenzylamine, α-methyl-; (R)-1-Amino-1-(2-cyanophenyl)ethane; (R)-Enantiomer of 2-(1-Aminoethyl)benzonitrile
EINECS	Contact for details

Quality Control

Our (R)-2-(-1-Amino-Ethyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.