Description

(1R)-1-[3-(Trifluoromethoxy)Phenyl]Pentylamine is a chiral amine building block featuring a trifluoromethoxy-substituted aromatic ring. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its specific stereochemistry and fluorine-containing moiety are critical for biological activity and metabolic stability. It is needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and receptor interactions.

Basic Information

Product Name	(1R)-1-[3-(Trifluoromethoxy)Phenyl]Pentylamine
CAS No.	1213516-55-2
Molecular Formula	C12H16F3NO
Molecular Weight	247.26 g/mol
Synonyms	(R)-1-[3-(Trifluoromethoxy)phenyl]pentan-1-amine; (1R)-1-[3-(Trifluoromethoxy)phenyl]pentylamine; (R)-1-(3-(Trifluoromethoxy)phenyl)pentan-1-amine; (R)-α-Methyl-3-(trifluoromethoxy)benzenepentylamine; 1-(3-Trifluoromethoxyphenyl)-1-pentylamine (R-enantiomer); (R)-3'-Trifluoromethoxyphenylpentylamine; (R)-TFMPA
EINECS	Contact for details

Quality Control

Our (1R)-1-[3-(Trifluoromethoxy)Phenyl]Pentylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.