Description

(3R)-3-Amino-3-(4-Bromophenyl)Propanenitrile CAS NO 1212985-72-2 is a chiral, non-natural amino acid derivative characterized by a nitrile group and a brominated aromatic ring. This compound serves as a critical chiral building block and intermediate in the synthesis of complex, biologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its bromophenyl moiety for structural diversity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organometallic chemistry.
• Peptidomimetics Research: Incorporated into peptide analogs to study structure-activity relationships and enhance metabolic stability.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity chiral intermediates.

Basic Information

Product Name	(3R)-3-Amino-3-(4-Bromophenyl)Propanenitrile
CAS No.	1212985-72-2
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	(R)-3-Amino-3-(4-bromophenyl)propanenitrile; (3R)-3-Amino-3-(4-bromophenyl)propionitrile; 4-Bromo-β-aminohydrocinnamomitrile (R)-enantiomer; (R)-3-Amino-3-(p-bromophenyl)propanenitrile; β-Amino-4-bromohydrocinnamomitrile (R)-form; (R)-4-Bromophenyl-β-aminopropionitrile; (R)-3-(4-Bromophenyl)-3-aminopropanenitrile
EINECS	Contact for details

Quality Control

Our (3R)-3-Amino-3-(4-Bromophenyl)Propanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.