Description

(S)-2-((tert-Butoxycarbonyl)Amino)-3-(2,4-Dinitrophenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a Boc-protected amine and a dinitrophenyl (DNP) side chain. This compound is a critical chiral building block in advanced pharmaceutical research, particularly for the synthesis of complex peptides and peptidomimetics. It is essential for medicinal chemists and process development scientists working on novel drug candidates in therapeutic areas such as oncology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique, labeled aromatic amino acid residue.
• Proteomics Research: Serves as a specialty amino acid derivative in the study of protein structure, function, and protein-ligand interactions.
• Bioconjugation: The reactive dinitrophenyl group can be utilized for labeling and conjugation applications in biochemical assays.
• Chemical Biology Tool: Employed in the development of enzyme inhibitors, receptor probes, and other bioactive molecules.
• Process Development: Used in route scouting and optimization for the scalable production of chiral compounds.

Basic Information

Product Name	(S)-2-((tert-Butoxycarbonyl)Amino)-3-(2,4-Dinitrophenyl)Propanoic Acid
CAS No.	1212864-47-5
Molecular Formula	C₁₄H₁₇N₃O₈
Molecular Weight	355.30 g/mol
Synonyms	Boc-Dnp-OH; Boc-2,4-Dinitrophenylalanine; (S)-2-(Boc-Amino)-3-(2,4-dinitrophenyl)propanoic acid; N-Boc-2,4-dinitro-L-phenylalanine; tert-Butyl (S)-(1-(2,4-dinitrophenyl)-1-carboxyethyl)carbamate; (S)-3-(2,4-Dinitrophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid; Boc-L-Dnp-OH; N-α-Boc-2,4-dinitro-L-phenylalanine
EINECS	Contact for details

Quality Control

Our production of (S)-2-((tert-Butoxycarbonyl)Amino)-3-(2,4-Dinitrophenyl)Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.