Description

cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-4-Enecarboxylic Acid is a specialized, high-purity building block designed for advanced organic synthesis. This compound is critical for the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams in the pharmaceutical, biotechnology, and fine chemical industries for peptide and peptidomimetic synthesis, where its unique structure enables precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex peptide-based drug candidates and therapeutic agents.
• Peptidomimetic Research: Used to introduce constrained cyclohexene scaffolds into peptide backbones, enhancing metabolic stability and biological activity.
• Combinatorial Chemistry: Serves as a versatile monomer in the generation of diverse chemical libraries for high-throughput screening.
• Protease Inhibitor Development: Incorporated into the structure of inhibitors targeting specific enzymes.
• Academic & Institutional Research: Employed in synthetic organic chemistry studies focused on novel methodologies and natural product synthesis.
• Bioconjugation: Potential use in creating labeled probes or antibody-drug conjugates (ADCs) due to its reactive carboxylic acid group and protected amine.

Basic Information

Product Name	cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-4-Enecarboxylic Acid
CAS No.	1212305-88-8
Molecular Formula	C22H21NO4
Molecular Weight	363.41 g/mol
Synonyms	Fmoc-cis-2-amino-cyclohex-4-ene-1-carboxylic acid; (1R,2S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)cyclohex-4-ene-1-carboxylic acid; (1S,2R)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)cyclohex-4-ene-1-carboxylic acid; Fmoc-Achc-OH (cis); cis-2-(Fmoc-amino)cyclohex-4-ene-1-carboxylic acid; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclohex-4-ene-1-carboxylic acid; cis-Fmoc-2-Amino-cyclohex-4-ene-carboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-4-Enecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage at 2-8°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.