Description

(1R*,2S*,5R*)-2-Benzyloxycarbonylamino-5-Hydroxy-Cyclohexanecarboxylic Acid CAS NO 1212264-04-4 is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound is a critical intermediate for the development of novel pharmaceuticals and bioactive molecules, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex drug candidates, peptide mimetics, and other fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid analog for constructing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Asymmetric Catalysis Research: Used as a ligand precursor or a chiral scaffold in the development of novel asymmetric catalysts and auxiliaries.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules on scale.
• Academic Research: Utilized in university and institutional labs for methodological development in stereoselective synthesis and medicinal chemistry projects.

Basic Information

Product Name	(1R*,2S*,5R*)-2-Benzyloxycarbonylamino-5-Hydroxy-Cyclohexanecarboxylic Acid
CAS No.	1212264-04-4
Molecular Formula	C16H21NO5
Molecular Weight	307.34 g/mol
Synonyms	(1R*,2S*,5R*)-2-[(Benzyloxy)carbonyl]amino-5-hydroxycyclohexanecarboxylic acid; (1R*,2S*,5R*)-5-Hydroxy-2-[[(phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid; (1R*,2S*,5R*)-2-(Cbz-amino)-5-hydroxy-cyclohexanecarboxylic acid; (1R*,2S*,5R*)-2-[(Cbz)amino]-5-hydroxycyclohexanecarboxylic acid; Z-Protected Cyclohexyl Amino Acid Derivative; rel-(1R,2S,5R)-2-(((Benzyloxy)carbonyl)amino)-5-hydroxycyclohexanecarboxylic acid; Chiral Cbz-Amino Cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (1R*,2S*,5R*)-2-Benzyloxycarbonylamino-5-Hydroxy-Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere (nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.