Description

(3-Cyano-5-(Trifluoromethyl)Phenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates containing the trifluoromethyl and cyano pharmacophores, which are prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl coupling reactions.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through palladium-catalyzed polymerization or functionalization.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and diagnostics.
• Catalyst & Ligand Design: Acts as a starting material for synthesizing novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Research: A vital reagent for custom synthesis organizations (CSOs) and R&D laboratories working on proprietary chemical projects.

Basic Information

Product Name	(3-Cyano-5-(Trifluoromethyl)Phenyl)Boronic Acid
CAS No.	1212021-62-9
Molecular Formula	C8H5BF3NO2
Molecular Weight	214.94 g/mol
Synonyms	[3-Cyano-5-(trifluoromethyl)phenyl]boronic acid; 3-Cyano-5-(trifluoromethyl)benzeneboronic acid; (3-Cyano-5-trifluoromethylphenyl)boronic acid; Boronic acid, B-[3-cyano-5-(trifluoromethyl)phenyl]-; 5-Cyano-3-(trifluoromethyl)phenylboronic acid; 3-Trifluoromethyl-5-cyanophenylboronic acid; 1212021-62-9
EINECS	Contact for details

Quality Control

Our (3-Cyano-5-(Trifluoromethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.