Description

3-(Pentafluorosulfur)Phenylacetic Acid is a high-value, fluorinated aromatic building block characterized by its unique pentafluorosulfur (SF5) substituent. This compound matters for its role in advanced material science and pharmaceutical research, where the introduction of the SF5 group can dramatically alter the electronic properties, metabolic stability, and lipophilicity of target molecules. It is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients, as well as in materials science for developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for incorporating the metabolically stable and highly electronegative pentafluorosulfur group into novel drug candidates, potentially improving their bioavailability and target selectivity.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the SF5 moiety can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies, contributing to improved dielectric anisotropy, thermal stability, and optical performance.
• Polymer & Material Science: Employed to create specialty fluorinated polymers with enhanced chemical resistance, lower surface energy, and improved thermal properties for coatings and high-performance plastics.
• Organic Synthesis Building Block: A versatile reagent for cross-coupling reactions, esterifications, and amide bond formations to construct complex, fluorinated molecular architectures.

Basic Information

Product Name	3-(Pentafluorosulfur)Phenylacetic Acid
CAS No.	1211578-68-5
Molecular Formula	C8H5F5O2S
Molecular Weight	260.18 g/mol
Synonyms	3-(SF5)Phenylacetic Acid; [3-(Pentafluoro-λ6-sulfanyl)phenyl]acetic Acid; 2-[3-(Pentafluorosulfanyl)phenyl]acetic Acid; 3-(Pentafluorosulfur)benzeneacetic Acid; α-Carboxy-3-(pentafluorosulfanyl)toluene; SF5-Phenylacetic Acid; 3-SF5-C6H4-CH2COOH
EINECS	Contact for details

Quality Control

Every batch of 3-(Pentafluorosulfur)Phenylacetic Acid is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.