Description

5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methoxy-Methyl-Amide is a high-value trifluoromethylated pyridine derivative, a crucial building block in modern synthetic chemistry. Its core value lies in its ability to impart desirable metabolic stability and lipophilicity to target molecules, making it indispensable for advanced research and development. This compound is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a critical precursor in the design and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands that modify the properties and reactivity of metal centers.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where its electronic properties can be leveraged.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methoxy-Methyl-Amide
CAS No.	1211538-46-3
Molecular Formula	C10H10F3N2O2
Molecular Weight	247.19 g/mol
Synonyms	N-Methoxy-N-methyl-5-(trifluoromethyl)picolinamide; 5-(Trifluoromethyl)picolinic acid N-methoxy-N-methylamide; 5-Trifluoromethyl-2-pyridinecarboxylic acid methoxy(methyl)amide; Methoxy-methyl-amide of 5-trifluoromethyl-pyridine-2-carboxylic acid; 5-Trifluoromethylpicolinoyl N,O-dimethylhydroxylamine; N-Methoxy-N-methyl-5-(trifluoromethyl)pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methoxy-Methyl-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.