Description

2-(3-Fluoro-5-Nitrophenyl)Acetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive acetic acid side chain with electron-withdrawing fluoro and nitro substituents on the phenyl ring, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require sophisticated intermediates for developing new active ingredients, such as kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its fluorinated aromatic structure for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or functionalization agent for creating specialized polymers with unique electronic or surface properties.
• Chemical Synthesis: Acts as a versatile building block for further derivatization, including amide coupling, esterification, and nucleophilic aromatic substitution reactions.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands or organocatalysts for asymmetric synthesis.
• Life Science Reagents: Utilized in the preparation of fluorescent probes, biochemical tags, and other research tools.

Basic Information

Product Name	2-(3-Fluoro-5-Nitrophenyl)Acetic Acid
CAS No.	1211529-88-2
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	(3-Fluoro-5-nitrophenyl)acetic acid; 2-(3-Fluoro-5-nitrophenyl)ethanoic acid; 3-Fluoro-5-nitrophenylacetic acid; 2-(3-Fluoro-5-nitrophenyl)acetic acid; Acetic acid, 2-(3-fluoro-5-nitrophenyl)-; 1211529-88-2; α-(3-Fluoro-5-nitrophenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-5-Nitrophenyl)Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.