Description

1-Methoxy-2-Bromo-4-(Pentafluorosulfanyl)Benzene is a high-value, multi-functional aromatic building block featuring a unique pentafluorosulfanyl (SF5) group. This compound is prized for its role in advanced material science and pharmaceutical research, where its distinct electronic and steric properties are leveraged to modulate the characteristics of target molecules. It is primarily utilized by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly where the SF5 group is used to enhance metabolic stability and lipophilicity.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides, where the SF5 moiety can improve biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its polarizable structure contributes to desired electro-optical properties.
• Polymer & Resin Modification: Used to incorporate fluorine and bromine functionalities into polymers, enhancing properties like chemical resistance, thermal stability, and flame retardancy.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Ligand & Catalyst Development: Useful for synthesizing specialized ligands for catalysis, leveraging the strong electron-withdrawing nature of the SF5 group.

Basic Information

Product Name	1-Methoxy-2-Bromo-4-(Pentafluorosulfanyl)Benzene
CAS No.	1211514-99-6
Molecular Formula	C7H4BrF5OS
Molecular Weight	311.07 g/mol
Synonyms	2-Bromo-1-methoxy-4-(pentafluoro-λ6-sulfanyl)benzene; 2-Bromo-4-(pentafluorosulfanyl)anisole; 4-Bromo-3-methoxybenzenesulfonyl pentafluoride; 1-Bromo-2-methoxy-5-(pentafluorosulfanyl)benzene; 2-Bromo-α,α,α,α',α'-pentafluoro-4-methoxybenzenesulfane; SF5-Anisole derivative
EINECS	Contact for details

Quality Control

Our 1-Methoxy-2-Bromo-4-(Pentafluorosulfanyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 19F, 13C), HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support custom synthesis and can tailor purity grades (e.g., >97%, >98%, >99%) to meet specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.