Description

2,2,2-Trifluoro-1-(2-Trifluoromethyl-Phenyl)-Ethylamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the trifluoromethyl and trifluoroethylamine groups, which are critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, particularly in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers and advanced organic materials with specific optical or electronic properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of polyfluorination on molecular conformation and reactivity.

Basic Information

Product Name	2,2,2-Trifluoro-1-(2-Trifluoromethyl-Phenyl)-Ethylamine
CAS No.	1211507-43-5
Molecular Formula	C9H7F6N
Molecular Weight	243.15 g/mol
Synonyms	α-(Trifluoromethyl)-2-(trifluoromethyl)benzeneethanamine; 1-(2-(Trifluoromethyl)phenyl)-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-[2-(trifluoromethyl)phenyl]ethan-1-amine; 2-(Trifluoromethyl)-α-(trifluoromethyl)benzeneethanamine; 1-(2-Trifluoromethylphenyl)-2,2,2-trifluoroethylamine; (2-(Trifluoromethyl)phenyl)(trifluoromethyl)methylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(2-Trifluoromethyl-Phenyl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.