Description

Ethyl 4-Fluoro-2-Nitrophenylacetate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent, makes it a versatile precursor for constructing complex pharmacophores and agrochemical intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce specific functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can improve pesticidal activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with tailored electronic or optical properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex fluorinated dyes and pigments used in high-performance applications.
• Academic & Contract Research: Employed in medicinal chemistry and process development research within academic institutions and contract research organizations (CROs).

Basic Information

Product Name	Ethyl 4-Fluoro-2-Nitrophenylacetate
CAS No.	1209007-72-6
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	Ethyl (4-Fluoro-2-nitrophenyl)acetate; 2-Nitro-4-fluorophenylacetic Acid Ethyl Ester; Acetic acid, 2-(4-fluoro-2-nitrophenyl)-, ethyl ester; 4-Fluoro-2-nitrophenylacetic Acid Ethyl Ester; Ethyl 2-(4-fluoro-2-nitrophenyl)acetate; (4-Fluoro-2-nitrophenyl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-2-Nitrophenylacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global B2B clients. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the nitro and ester functional groups, it should be stored separately from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.